| Source |
 |
 |
 |
| Evaluation of respiratory effects of thermal decomposition products following single and repeated exposures of guinea pigs. |
No |
No |
No |
| Organic solvent neurotoxicity, facts and research needs. |
No |
No |
No |
| Toxicity of the components of styrene polymers: Polystyrene, acrylonitrile-butadiene-styrene (ABS) and styrene-butadiene-rubber (SBR). Reactants and additives. |
No |
No |
No |
| Comparison of breath, blood and urine concentrations in the biomonitoring of environmental exposure to 1,3-butadiene, 2,5-dimethylfuran, and benzene |
No |
No |
No |
| Biological exposure limits estimated from relations between occupational styrene exposure during a workweek and excretion of mandelic and phenylglyoxylic acids in urine. |
No |
No |
No |
| Blood styrene concentrations in a "normal" population and in exposed workers 16 hours after the end of the workshift. |
No |
No |
No |
| Time/toxicity relationships in short-term static, dynamic, and plug-flow bioassays. |
No |
No |
No |
| Environmental fate and effects of styrene |
No |
No |
No |
| Chronic toxicity of acrylonitrile and acetonitrile to Daphnia magna in 14-d and 21-d toxicity tests |
No |
No |
No |
| Neuroendocrine effects of styrene on occupationally exposed workers. |
No |
Yes |
No |
| Cytogenetic and hematological effects in plastics workers exposed to styrene. |
No |
No |
No |
| Spontaneous abortions and congenital malformations among the wives of men occupationally exposed to organic solvents. |
No |
No |
No |
| Monitoring occupational exposure to styrene from hemoglobin adducts and metabolites in blood |
No |
No |
No |
| Development of Emission Factors for Polycarbonate Processing |
No |
No |
No |
| Exposure to styrene. Uptake, distribution, metabolism and elimination in man. |
No |
No |
Yes |
| Styrene exposure and the liver. |
No |
No |
No |
| Behavioral Changes After Long-Term Exposure to Organic Solvents and Their Mixtures: Determining Factors and Research Results. |
No |
No |
No |
| Acrylonitrile. |
No |
No |
No |
| Audiometric Findings in Workers Exposed to Low Levels of Styrene and Noise |
No |
No |
No |
| Sampling and analysis of volatile organic compounds evolved during thermal processing of acrylonitrile butadiene styrene composite resins |
No |
Yes |
Yes |
| Characterization of Emissions from Diffusion Flare Systems |
No |
No |
No |
| Exposure assessment for a study of workers exposed to acrylonitrile. I. Job exposure profiles: A computerized data management system. |
No |
No |
No |
| Species differences in the distribution of inhaled butadiene in tissues. |
No |
No |
No |
| Concentrations and Sources of Volatile Organic Compounds in Urban Domestic and Public Microenvironments |
No |
No |
No |
| Investigation of a Long-Term Sampling Period for Monitoring Volatile Organic Compounds in Ambient Air |
No |
No |
No |
| Styrene Oxide in Blood, Hemoglobin Adducts, and Urinary Metabolites in Human Volunteers Exposed to C-Styrene Vapors |
No |
No |
No |
| Concentrations and Sources of VOCs in Urban Domestic and Public Microenvironments |
No |
No |
No |
| Environmental exposure to 1,3-butadiene: A human health perspective |
No |
No |
No |
| Environmental exposure to volatile organic compounds among workers in Mexico City as assessed by personal monitors and blood concentrations |
No |
No |
No |
| An Assessment of Air Toxics in Minnesota |
No |
No |
No |
| Biomarkers: Coming of age for environmental health and risk assessment |
No |
No |
No |
| Recent Chemical Exposures and Blood Volatile Organic Compound Levels in a Large Population-Based Sample |
No |
No |
No |
| A comprehensive evaluation of the potential health risks associated with occupational and environmental exposure to styrene.[erratum appears in J Toxicol Environ Health B Crit Rev 2002 Jul-Sep;5(3):335]. [Review] [223 refs] |
No |
No |
No |
| Biodegradation of styrene in samples of natural environments. |
No |
No |
No |
| Environmental contaminants and reproductive toxicity: A review |
No |
No |
No |
| Environmental pollutants in relation to complications of pregnancy |
No |
No |
No |
| Dermal absorption of organic chemical vapors in rats and humans. |
No |
No |
No |
| Chronic toxicity and three-generation reproduction study of styrene monomer in the drinking water of rats. |
No |
No |
No |
| Respiratory morbidity of pattern and model makers exposed to wood, plastic, and metal products. |
No |
No |
No |
| Objectives, designs and populations of the European Asclepios study on occupational hazards to male reproductive capability. |
No |
No |
No |
| Exposure-effect and exposure-response relationships between occupational exposure to styrene and neuropsychological functions. |
No |
No |
No |
| Spontaneous abortions among women employed in the plastics industry. |
No |
No |
No |
| Cytogenetic evaluation of bone marrow cells from rats exposed to styrene vapor for one year. |
No |
No |
No |
| Alteration in the biliary and urinary excretion of acetaminophen metabolites by nephrotoxicants in rats. |
No |
No |
No |
| Change in semen quality and sperm chromatin structure following occupational styrene exposure. ASCLEPIOS.[comment]. |
No |
No |
No |
| Induced tolerance to acrylonitrile toxicity by prior acrylonitrile exposure. |
No |
No |
No |
| Effects of acrylonitrile on tissue glutathione concentrations in rat, mouse, and hamster. |
No |
No |
No |
| Occupational risk to male reproduction.[comment]. [Review] [17 refs] |
No |
No |
No |
| Possible role of lipid peroxidation in the actions of acrylonitrile on the adrenals, liver and gastrointestinal tract. |
No |
No |
No |
| Embryo/fetotoxicity of styrene in rats. |
No |
No |
No |
| VOC concentrations measured in personal samples and residential indoor, outdoor and workplace microenvironments in EXPOLIS-Helsinki, Finland |
No |
No |
No |
| Evaluation of the nephrotoxic potential of styrene in man and in rat. |
No |
No |
No |
| Review of cadmium in plastic waste in Sweden. |
No |
No |
No |
| Case-cohort study of styrene exposure and ischemic heart disease. |
No |
No |
No |
| Adrenal-dependent leucopenia after short-term exposure to various airborne irritants in rats. |
No |
No |
No |
| Emissions from processing thermoplastics |
No |
No |
Yes |
| Biological monitoring of acrylonitrile exposure. |
No |
No |
No |
| Expression of ras (p21) protein in plasma from exposed workers and from patients with lung disease. |
No |
No |
No |
| Acrylonitrile inhalation in rats: II. Excretion of thioethers and thiocyanate in urine. |
No |
No |
No |
| Toxicity of acrylonitrile in a human neuroblastoma cell line and its effect on glutathione and glutathione-S-transferase. |
No |
No |
No |
| Use of duckweed (Lemna minor L.) growth inhibition test to evaluate the toxicity of acrylonitrile, sulphocyanic sodium and acetonitrile in China |
No |
No |
No |
| Effect of styrene on monoamine oxidase B activity in rat brain. |
No |
No |
No |
| The effects of acrylonitrile on hemoglobin and red cell metabolism. |
No |
No |
No |
| Acrylonitrile-induced gastric mucosal necrosis: role of gastric glutathione. |
No |
No |
No |
| Effect of acrylonitrile on the procoagulant activity of rat lung. |
No |
No |
No |
| Toxicology and carcinogenesis studies of acrylonitrile (CAS No. 107-13-1) in B6C3F1 mice (gavage studies). |
No |
No |
No |
| Intervention study on acquired color vision deficiencies in styrene-exposed workers. |
No |
No |
No |
| Styrene: Environmental health criteria 26. |
No |
No |
No |
| Controlling air emissions from equipment leaks: Results of industry wide surveys of 1,3-butadiene, ethylene oxide, and phosgene production facilities. |
No |
No |
No |
| Penetration of protective clothing materials by 1,2-dibromo-3-chloropropane, ethylene dibromide, and acrylonitrile. |
No |
No |
No |
| The TEAM study: Personal exposures to toxic substances in air, drinking water, and breath of 400 residents of New Jersey, North Carolina, and North Dakota. |
No |
No |
No |
| Reproductive and developmental toxicity of styrene. |
No |
No |
No |
| Ototoxic effects of occupational exposure to styrene and co-exposure to styrene and noise. |
No |
No |
No |
| Experimental pharmacokinetics and toxicology of acrylonitrile. |
No |
No |
No |
| Occupational exposure to styrene in Norway, 1972-1996. |
No |
No |
No |
| Hemoglobin adducts from acrylonitrile and ethylene oxide in cigarette smokers: effects of glutathione S-transferase T1-null and M1-null genotypes. |
No |
No |
No |
| Induction of a permeability transition in rat kidney mitochondria by pentachlorobutadienyl cysteine: a beta-lyase-independent process. |
No |
No |
No |
| Refinements to physiologically-based pharmacokinetic model for styrene.[comment]. |
No |
No |
No |
| Synthesis and characterization of peptide adducts for use in monitoring human exposure to acrylonitrile and ethylene oxide. |
No |
No |
No |
| Polycyclic aromatic hydrocarbons in combustion residues from 1,3-butadiene |
No |
No |
No |
| Changes in cellular immunity among workers occupationally exposed to styrene in a plastics lamination plant. |
No |
No |
No |
| Cumulative exposure to styrene and visual functions. |
No |
No |
No |
| A study on toxic organic emissions from batch combustion of styrene |
No |
No |
No |
| Styrene: An occupational hazard. |
No |
No |
No |
| Analysis of the spectra of genetic activity in short-term tests. |
No |
No |
No |
| Styrene-induced peripheral neuropathy. |
No |
No |
No |
| Chemoprotection and interindividual differences in response to biological reactive intermediates. [Review] [27 refs] |
No |
No |
No |
| Serum hepatic biochemical activity in two populations of workers exposed to styrene. |
No |
No |
No |
| Relation between colour vision loss and occupational styrene exposure level. |
No |
No |
No |
| Relation between colour vision loss and occupational styrene exposure level.[comment]. |
No |
No |
No |
| The toxicity of styrene to the nasal epithelium of mice and rats: studies on the mode of action and relevance to humans. |
No |
No |
No |
| Acute acrylonitrile toxicity: studies on the mechanism of the antidotal effect of D- and L-cysteine and their N-acetyl derivatives in the rat. |
No |
No |
No |
| Haemoglobin adducts of epoxybutanediol from exposure to 1,3-butadiene or butadiene epoxides. |
No |
No |
No |
| Hemoglobin adducts as biomarkers of 1,3-butadiene in occupationally low exposed Italian workers and a few diesel-exposed miners. |
No |
No |
No |
| Species differences in the metabolism of olefins: implications for risk assessment. [Review] [22 refs] |
No |
No |
No |
| Assessment of the acute acrylonitrile-induced neurotoxicity in rats. |
No |
No |
No |
| Determination of hemoglobin adducts in humans occupationally exposed to acrylamide. |
No |
No |
No |
| Clastogenic effects of 1,3-butadiene and its metabolites 1,2-epoxybutene and 1,2,3,4-diepoxybutane in splenocytes and germ cells of rats and mice in vivo. |
No |
No |
No |
| Effect of dosing vehicle on the toxicity and metabolism of unsaturated aliphatic nitriles. |
No |
No |
No |
| Effect of subchronic ethanol ingestion on styrene-induced damage to the tracheal and pulmonary epithelium of the rat. |
No |
No |
No |
| Chronic toxicity/oncogenicity study of styrene in CD-1 mice by inhalation exposure for 104 weeks. |
No |
No |
No |
| Acrylonitrile: in vivo metabolism in rats and mice. |
No |
No |
No |
| Acrylonitrile-induced gastrointestinal hemorrhage and the effects of metabolism modulation in rats. |
No |
No |
No |
| Dose dependence of covalent binding of acrylonitrile to tissue protein and globin in rats. |
No |
No |
No |
| Relative neurotoxicological properties of five unsaturated aliphatic nitriles in rats. |
No |
No |
No |
| Comparison of toluene-induced and styrene-induced hearing losses. |
No |
No |
No |
| Mutagenic potential of adenine N(6) adducts of monoepoxide and diolepoxide derivatives of butadiene. |
No |
No |
No |
| Acrylonitrile enhances H2O2-mediated DNA damage via nitrogen-centered radical formation. |
No |
No |
No |
| NTP announces bioassay results. |
No |
No |
No |
| Fertility outcome in some Swedish groups occupationally exposed to chemicals. |
No |
No |
No |
| Biological markers of acute acrylonitrile intoxication in rats as a function of dose and time. |
No |
No |
No |
| Evaluation of three retrospective exposure assessment methods. |
No |
No |
No |
| Solvent ototoxicity in the rat and guinea pig. |
No |
No |
No |
| Hemoglobin adducts of acrylamide and acrylonitrile in laboratory workers, smokers and nonsmokers. |
No |
No |
No |
| Metabolic capacity and interindividual variation in toxicokinetics of styrene in volunteers. |
No |
No |
No |
| Sperm production of men working under heavy-metal or organic-solvent exposure. |
No |
No |
No |
| Toxicology and epidemiology of 1,3-butadiene. [Review] [239 refs] |
No |
No |
No |
| Glutamine synthetase activity in rat urine as sensitive marker to detect S3 segment-specific injury of proximal tubule induced by xenobiotics. |
No |
No |
No |
| Effects of prenatal and postnatal exposure to styrene dimers and trimers on reproductive function in rats. |
No |
No |
No |
| A mechanistic assessment of 1,3-butadiene diepoxide-induced inhibition of uterine deciduoma proliferation in pseudopregnant rats. |
No |
No |
No |
| Acute behavioral effects of solvent exposure. |
No |
No |
No |
| Clinical and neurobehavioural study of the acute and chronic neurotoxicity of styrene. |
No |
No |
No |
| Neuropsychiatric effects of low exposure to styrene. |
No |
No |
No |
| Raised serum bile acid concentrations after occupational exposure to styrene: A possible sign of hepatotoxicity. |
No |
No |
No |
| Peripheral markers of neurochemical function among workers exposed to styrene. |
No |
No |
No |
| Macromolecular adducts caused by environmental chemicals. |
No |
No |
No |
| Glutamine transaminase K intranephron localization in rats determined by urinary excretion after treatment with segment-specific nephrotoxicants. |
No |
No |
No |
| Styrene hepatotoxicity in rats treated by inhalation or intraperitoneally: a structural investigation. |
No |
No |
No |
| Mortality study of workers exposed to dimethylformamide and/or acrylonitrile. |
No |
No |
No |
| Health profiles of workers exposed to acrylonitrile. |
No |
No |
No |
| Unusual occupational toxins. [Review] [145 refs] |
No |
No |
No |
| Evaluation of a possible styrene-induced damage to the haematopoietic tissues in the rat. |
No |
No |
No |
| Possible impact of human CYP2E1 polymorphisms on the metabolism of acrylonitrile. |
No |
No |
No |
| Acquired dyschromatopsia among styrene-exposed workers. |
No |
No |
No |
| Effect of chronic exposure to acrylonitrile on subjective symptoms. |
No |
No |
No |
| Biomonitoring of occupational exposure to styrene in a plastics lamination plant. |
No |
No |
No |
| Species differences in acrylonitrile metabolism and toxicity between experimental animals and humans based on observations in human accidental poisonings. [Review] [37 refs] |
No |
No |
No |
| Comparative chronic toxicity and carcinogenicity of acrylonitrile by drinking water and oral intubation to Spartan Sprague-Dawley rats. |
No |
No |
No |
| Chronic toxicity/oncogenicity study of styrene in CD rats by inhalation exposure for 104 weeks. |
No |
No |
No |
| Effects of prenatal exposure to styrene on neurochemical levels in rat brain. |
No |
No |
No |
| Characterization of hepatocellular resistance and susceptibility to styrene toxicity in B6C3F1 mice. |
No |
No |
No |
| Hemoglobin adducts of epoxybutene in workers occupationally exposed to 1,3-butadiene. |
No |
No |
No |
| Effects of styrene monomer and trimer on gonadal sex differentiation of genetic males of the frog Rana rugosa. |
No |
No |
No |
| Hemoglobin adducts of ethylene oxide, propylene oxide, acrylonitrile and acrylamide-biomarkers in occupational and environmental medicine. |
No |
No |
No |
| Three-generation reproduction study of rats receiving acrylonitrile in drinking water. |
No |
No |
No |
| Urinary excretion of acrylonitrile and its metabolites in rats. |
No |
No |
No |
| Somatic and germ cell effects in rats and mice after treatment with 1,3-butadiene and its metabolites, 1,2-epoxybutene and 1,2,3,4-diepoxybutane. |
No |
No |
No |
| Butadiene: species comparison for metabolism and genetic toxicology. [Review] [94 refs] |
No |
No |
No |
| Mechanism of neurobehavioral alteration. [Review] [22 refs] |
No |
No |
No |
| Effects of low-level occupational exposure to styrene on color vision: dose relation with a urinary metabolite. |
No |
No |
No |
| Lymphocyte phenotype analysis and chromosome aberration frequency of workers occupationally exposed to styrene, benzene, polycyclic aromatic hydrocarbons or mixed solvents. |
No |
No |
No |
| Testosterone in sera of workers exposed to acrylonitrile. |
No |
No |
No |
| Human cytogenetic biomonitoring of occupational exposure to 1,3-butadiene. |
No |
No |
No |
| The rodent dominant lethal assay: regulatory questions concerning appraisal of an industrial chemical as exemplified by 1,3-butadiene. |
No |
No |
No |
| Reproductive toxicity of 1,3-butadiene in the mouse: cytogenetic analysis of chromosome aberrations in first-cleavage embryos and flow cytometric evaluation of spermatogonial cell killing. |
No |
No |
No |
| Diepoxybutane cytotoxicity on mouse germ cells is enhanced by in vivo glutathione depletion: a flow cytometric approach. |
No |
No |
No |
| Genotoxic effects of butadiene in mouse lung cells detected by an ex vivo micronucleus test. |
No |
No |
No |
| Influence of polymorphisms of the human glutathione transferases and cytochrome P450 2E1 enzyme on the metabolism and toxicity of ethylene oxide and acrylonitrile. |
No |
No |
No |
| Effects of prenatal styrene exposure on postnatal development and brain serotonin and catecholamine levels in rats. |
No |
No |
No |
| Functional and morphological effects of styrene on the auditory system of the rat. |
No |
No |
No |
| Sperm-FISH analysis and human monitoring: a study on workers occupationally exposed to styrene. |
No |
No |
No |
| Effects of various pretreatments on the acute nephrotoxic potential of styrene in Fischer-344 rats. |
No |
No |
No |
| Model-based time extrapolation for quantal response studies. |
No |
No |
No |
| Bone marrow and renal injury associated with haloalkene cysteine conjugates in calves. |
No |
No |
No |
| Analysis of micronuclei induced by 1,3-butadiene and its metabolites using fluorescence in situ hybridization. |
No |
No |
No |
| Exposure to hydrocarbons and renal disease: an experimental animal model. |
No |
No |
No |
| Combined effects of exposure to styrene and ethanol on the auditory function in the rat. |
No |
No |
No |
| Styrene-induced hearing loss: a membrane insult. |
No |
No |
No |
| Effects of acrylonitrile on rat liver cytochrome P-450, benzo(a)pyrene metabolism and serum hormone levels. |
No |
No |
No |
| Modulation of acrylonitrile-induced embryotoxicity in vitro by glutathione depletion. |
No |
No |
No |
| Combined effects of noise and styrene exposure on hearing function in the rat. |
No |
No |
No |
| Testicular effects of acrylonitrile in mice. |
No |
No |
No |
| Health risk assessment of chemical mixtures from a research perspective. |
No |
No |
No |
| Occupational contact dermatitis due to acrylonitrile. |
No |
No |
No |
| Inhalation toxicity and carcinogenicity of isoprene in rats and mice: comparisons with 1,3-butadiene. [Review] [22 refs] |
No |
No |
No |
| Review of reproductive and developmental toxicity of 1,3-butadiene. [Review] [26 refs] |
No |
No |
No |
| Possible reproductive toxicity of styrene in peripubertal male mice. |
No |
No |
No |
| Impairment of neurobehavioral function and color vision loss among workers exposed to low concentration of styrene--a review of literatures. [Review] [24 refs] |
No |
No |
No |
| Is the aged rat ear more susceptible to noise or styrene damage than the young ear?. |
No |
No |
No |
| Respiratory tract dosimetry modeling of air toxics. |
No |
No |
No |
| Study of cancer incidence and air toxics controllability in five U.S. Cities. |
No |
No |
No |
| Effects of inhaled acrylic acid derivatives in rats. |
No |
No |
No |
| A study on reference standard for cytotoxicity assay of biomaterials. |
No |
No |
No |
| Studies on the molecular toxicology of buta-1,3-diene and isoprene epoxides. |
No |
No |
No |
| Comparison of the mutagenic potency of 1,3-butadiene at the hprt locus of T-lymphocytes following inhalation exposure of female B6C3F1 mice and F344 rats. |
No |
No |
No |
| Comparative toxicity of known and putative metabolites of 1, 3-butadiene in human CD34(+) bone marrow cells. |
No |
No |
No |
| Color vision: a sensitive indicator of exposure to neurotoxins. [Review] [50 refs] |
No |
No |
No |
| Styrene-induced changes in amacrine retinal cells: an experimental study in the rat. |
No |
No |
No |
| Sites and mechanisms for uptake of gases and vapors in the respiratory tract. [Review] [25 refs] |
No |
No |
No |
| Effects of the structure of a toxicokinetic model of butadiene inhalation exposure on computed production of carcinogenic intermediates. |
No |
No |
No |
| Risk assessment for butadiene: introductory and summary comments. |
No |
No |
No |
| The role of cytochromes P-450 in styrene induced pulmonary toxicity and carcinogenicity. |
No |
No |
No |
| Compilation of air pollutant emission factors, third edition, supplement 13 (including supplements 1-7). |
No |
No |
No |
| A health risk benchmark for the neurologic effects of styrene: comparison with NOAEL/LOAEL approach. |
No |
No |
No |
| Effect of inhaled industrial chemicals on systemic and local immune response. |
No |
No |
No |
| Biochemical and developmental effects in rats following in utero exposure to acrylonitrile: a preliminary report. |
No |
No |
No |
| Pulmonary toxicity of acrylonitrile: covalent interaction and effect on replicative and unscheduled DNA synthesis in the lung. |
No |
No |
No |
| Endocrine Disruptors and the Environment |
No |
No |
No |
| Health assessment document for acrylonitrile. |
No |
No |
No |
| Ambient Water Quality Criteria for the Protection of Human Health: Acrylonitrile |
No |
No |
No |
| TRACI: The Tool for the Reduction and Assessment of Chemical and Other Environmental Impacts |
No |
No |
No |
| Intake fraction for multimedia pollutants: a tool for life cycle analysis and comparative risk assessment |
No |
No |
Yes |
| ETH-ESU 96 Unit processes database. In: Simapro6 |
No |
No |
Yes |
| Franklin database. In: Simapro6 |
No |
No |
Yes |
| Compilation of cancer potency factors and acceptable daily intake values |
No |
No |
Yes |
| Human toxicity potentials for life cycle analysis and toxics release inventory risk screening. |
No |
Yes |
No |
| IDEMAT. In: Simapro6 |
No |
No |
No |
| Data Archive library. In: SimaPro6 |
No |
No |
No |
| Industry Data library. In: SimaPro6 |
No |
Yes |
No |
| SimaPro 6 |
No |
No |
Yes |
| National-Scale Air Toxics Assessment for 1996: Appendix H Estimating Carcinogenic Potency for Mixtures of Polycyclic Organic Matter (POM) for the 1996 National-Scale Assessment. |
No |
No |
Yes |
| Locating and estimating air emissions from sources of polycyclic organic matter |
No |
No |
Yes |
| Toxic release inventory public data release |
No |
Yes |
No |
| Ecoprofiles of the European plastics industry, report 13 , Co-polymers of Acrylonitrile-Butadiene- Styrene (ABS) and Styrene-Acrylonitrile (SAN), October 1997. |
No |
No |
Yes |
| Biological monitoring in occupational expsoure to low levels of 1,3-butadiene |
No |
No |
Yes |